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      Acute and chronic cardiotoxicity in Leiden

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      November 14, 2019

      Thursday   9:00 PM

      Galileiweg 8, 2333
      Leiden, Zuid-Holland

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      Acute and chronic cardiotoxicity

      The course is a two-day laboratory workshop in Leiden. This training instructs the attendee in best practices procedures for in silico and in vitro assays related to acute and chronic cardiotoxicity. Draft agenda : here Participants will learn among other things: Regulatory context to apply these methodologies as well as strength, weaknesses and future prospects (UCB - Dr Delaunois) Cell handling of human iPSC-derived cardiomyocytes (e.g. thawing procedure, cells seeding) (NCardia) Preparation of cryopreserved hiPSC-derived cardiomyocytes in 48/96 or 348 well plates (NCardia) Exposure of cells with cardiotoxic compounds using different readouts such as CiPA-like MEA (Micro-electrode array) and calcium flux assay (NCardia) Risk Assessment, validation, analysis interpretation and decision making using HiPS-cells for early drug discovery and development (Jannsen Pharma - Dr. Kreir) In silico assessment of the effects of various compounds in MEA/hiPSC-CM assays: modelling and numerical simulations (inria) The training will start with half day lectures and will be followed by 1.5 days of practical training (Hands on-training) where participants, divided in small group will get the chance to manipulate and see the critical steps of the methods with the experts. This is a perfect way to quickly approach a method, as well as data analysis and interpretation. The training will only take place if a minimum of 4 participants is reached. Registration fee includes the participant booklet, catering and social dinner. FAQ What's the refund and cancellation policy? Refunds are available only if Altertox Academy cancels the event. This is stated on the participant’s receipt once registered. However, tickets may be transferable if the ticket holder is unable to attend the event. In principle the ticket may only be transferred within the same price category but a final decision will be made at Altertox Academy's discretion. Do I actually manipulate in the lab? Each hands-on training is scheduled to last for 2-Days. In these two days, the hands-on trainings encompass 20% Lectures and 80% Laboratory practices. In other words, for about more than a day and a half of the trainings each participant will able to actively manipulate in the laboratory in small groups of 3-4 people. Therefore, some preliminary knowledge for cell culture in the lab is mandatory. What is the difference between “private” sector and “non-private” sector? The participant must choose the "private” sector in case his/her organization has any commercial activities e.g. selling products or services to third parties. What is a "webinar" ticket? The webinar ticket allows you to follow live the lectures that take place in the morning of the first day of training through an online platform specified by Altertox Academy before the training begins. 

      Categories: Science

      Event details may change at any time, always check with the event organizer when planning to attend this event or purchase tickets.