Bioengineering Department Seminar

Bioengineering Department Seminar Seminar | February 15 | 12-1 p.m. | 106 Stanley Hall
Speaker/Performer: Stephen Fong, Virginia Commonwealth University Sponsor: Bioengineering (BioE)
Spring 2012 Seminar Series

Wednesday, February 15
12noon - 1:00pm
106 Stanley Hall, UC Berkeley

An integrated computational-experimental approach to metabolic engineering

Stephen Fong
Associate Professor of Chemical and Life Science Engineering
Fellow, Center for the Study of Biological Complexity
Virginia Commonwealth University

Metabolic engineering is an application driven field that seeks to modify native cellular function by a variety of means. Given recent advances in experimental and computational methodologies, the scope and approaches for metabolic engineering have continued to evolve. In particular, one developing approach is to utilize computational modeling to analyze and predict cellular designs for experimental implementation. This talk will focus on work within our group for a computational-experimental approach to metabolic engineering that uses metabolic modeling in conjunction with high-throughput data and molecular biology techniques. Specifically, background and experimental testing of constraint-based metabolic models will be discussed as a platform for computational strain design. Methodology improvements based on algorithm development and experimental data integration can be used to improve the utility of a metabolic model and finally, progress towards complete computational design and synthetic implementation will be presented.

Hosted by Professor John Dueber
Event Contact: 510-642-5833